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Science Cytology

Protein Kinase Functions

edited by James Woodgett

Publisher
Oxford University Press
Initial publish date
Aug 2000
Category
Cytology
  • Paperback / softback

    ISBN
    9780199637706
    Publish Date
    Aug 2000
    List Price
    $294.00

Classroom Resources

Where to buy it

Out of print

This edition is not currently available in bookstores. Check your local library or search for used copies at Abebooks.

Description

Since the publication of Protein Kinases in 1994 many novel protein kinases have been discovered, but perhaps more importantly there have been dramatic advances in our understanding of the cellular functions of this remarkably diverse class of proteins. Protein Kinase Functions is not just an update of the previous edition but provides a new focus on the context and function of protein kinases, thus reflecting the recent advances in kinase biology. Chapters on genetic approaches to protein kinase functions, the MAP kinase pathway, and cyclin-dependent kinases have been completely updated and new topics covered in depth are: phosphatidylinositol 3-kinase signalling, JAK-STAT signalling, suppression of tyrosine kinases by the SOCS family proteins, the TGFss superfamily, and the involvement of protein kinases in response to DNA damage. Throughout, emphasis is placed not on individual kinases, but on the functional aspects of the whole system and the relationship between processes and molecules. It is the aim of Protein Kinase Functions to enable the reader to assimilate, compare, and integrate the molecular machinery used by cells to co-ordinate and respond to their environments.

About the author

Contributor Notes

James Woodgett is at Ontario Cancer Institute, University of Toronto.

Editorial Reviews

" ... the book can be thoroughly recommended to anyone interested in the field." Trends in Cell Biology