Since the end of World War II, BCG has almost exclusively held the stage in discussions of the problem of protective vaccination against tuberculosis. Yet inoculation with BCG is not the only method by means of which an immunity can be induced even in tuberculosis. It is also true that opinions by no means agree as to the value of BCG vaccination; particularly in the field of veterinary medicine an almost entirely unfavourable evaluation of the procedure has recently prevailed. As a result BCG vaccination is no longer accepted to such an emphatic degree today. Investigations with the objective of improving or replacing the method are claiming greater attention, especially in Germany.

In the monograph the authors present a review of current problems in the field of vaccination in tuberculosis, and correlate the extensive experimental and clinical material including the work published in recent years. At a time when new developments seem to be making headway, this account will provide a useful summary of information and a basis for further work.

RICHARD PRIGGE is Director of the State Institute for Experimental Therapy, Paul Ehrlich Institute, Frankfurt am Main.

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GUNTHER HEYMANN is a Scientific Member of the Institute.

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H. Chandler Elliott is Associate Professor of Medicine, University of Nebraska.

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